Furthermore, the results of a clinical study evaluating the relationship between DC infiltration and VEGF expression in NSCLC (132 primary NSCLC treated with surgery) showed that the mean number of infiltrating DCs in the VEGF high expression group was lower than that in the low expression group 84, indicating that VEGF may regulate the infiltration of DC into NSCLC tumor (Figure 3A). This evidence concerns the gene VEGFA and neoplasm.