Cox regression multivariate analysis also revealed that HMGA2 could be an independent prognostic factor for shorter OS (HR = 1.11, 95% CI:1.04-1.17, p < 0.01; Figure 3G) and DFS (HR = 1.13, 95% CI:1.04-1.22, p < 0.01; Figure 3H) in ccRCC patients. The gene discussed is HMGA2; the disease is nonpapillary renal cell carcinoma.