On the other hand, Gopalan et al. did not report any differences on genes involved in the regulation of the immune and neurophysiological function (IL-2 and BDNF) between “exercisers” (i.e., 24-weeks, 4 sessions/week 20–45 min + 15–30 min yoga) and “non-exercisers” children with HIV infection (29). The gene discussed is BDNF; the disease is HIV infectious disease.