It plays a carcinogenic role in luminal A and triple-negative breast cancers, and some studies have shown that TALNEC2 knockout can inhibit cell viability and community integration in luminal A and triple-negative breast cancers 49 Polycomb histone methyltransferase enhancer 2 (Polycomb histone methyltransferase enhancer of zeste homolog 2, EZH2) is considered as a key marker of invasive breast cancer 50. This evidence concerns the gene EZH2 and triple-negative breast carcinoma.