Studies have found that DANCR is negatively correlated with miR-758-3p, and down-regulation of DANCR can activate tumor suppressor miR-758-3p to play a tumor-suppressive role and promote apoptosis and autophagy of breast cancer cells: Promote the transcription and protein expression of Caspase-3, Caspase-9, Bcl-2, LC3B and ATG5 to inhibit the malignant proliferation of breast cancer cells 78. This evidence concerns the gene CASP9 and breast cancer.