Chung et al. found that the STK11/LKB1 signaling pathway regulates ADIPOQ/ adiponectin mediated AMPK activation, map1LC3B-II/LC3B-II release, and ULK1 (Unc-51 like kinase 1) activation, thus inducing autophagy to inhibit tumor progression 20. The gene discussed is STK11; the disease is neoplasm.