Also, work from our lab has shown that WNK1 inhibition in five different breast cancer cell lines MDA-MB-231, BT-549, BT-20, HCC1569, and HCC1419 significantly reduced the migratory capacity concomitantly with the reduction in N-cadherin protein expression (Jaykumar et al., 2021). This evidence concerns the gene CDH2 and breast carcinoma.