Paralleling findings in endothelial cells, WNK1 has been implicated in migration with epithelial-mesenchymal (EMT) features through knockdown studies in multiple cancer types, and also as a contributor to stem-like properties in metastatic breast cancers (Shyamasundar et al., 2016; Hung et al., 2017; Pio et al., 2017). The gene discussed is WNK1; the disease is cancer.