But the expression level of NFKBIA did not significantly alter in blood monocyte-derived macrophages infected with S. agalactiae (67), blood leukocytes infected with Staphylococcus aureus (68) and E. coli (69), circulating leukocytes with clinical or subclinical mastitis in the UK (25), and the Chinese Holstein mammary fibroblasts infected with S. aureus (70). The gene discussed is NFKBIA; the disease is mastitis.