As presented in Figure 5A, only 13 of 30 hub genes (CCND1, VEGFA, CDC42, EZH2, NRAS, CASP3, PPP2R1A, COL1A1, WWP1, COL1A2, CUL2, COL3A1, and COL5A1) were significantly upregulated in breast cancer, indicating that they might be the potential target genes of let-7b-5p, miR-195-5p, miR-29a-3p, miR-26a-5p, and miR-26b-5p. This evidence concerns the gene COL1A1 and breast cancer.