For example, Al-Harbi et al. (2018)showed that let-7b-5p inhibited the cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 suppression ; Marques et al. (2018)suggested that miR-195-5p served as a tumor suppressor in invasive breast cancer ); Zhao et al. (2017) found that miR-29a-3p suppressed MCF-7 cell growth by decreasing expression of tumor necrosis factor receptor 1. The gene discussed is TNFRSF1A; the disease is invasive breast carcinoma.