CD4 and neoplasm: The findings indicated that the high-risk group was negatively correlated with tumor-infiltrating immune cells, such as neutrophils, M1 macrophages, plasmacytoid dendritic cells, CD4+ T cells, and CD8+ T cells (Figures 3B–F), whereas it was positively correlated with cancer-associated fibroblasts and M2 macrophages (Supplementary Figure S4).