It has been revealed that lncRNA MIR4435-2HG may be a potential biomarker for the treatment and prognosis of liver cancer by upregulating the expression of B3GNT5 (Zhu et al., 2022) and may be a novel therapeutic target in gastric carcinoma by targeting the miR-138-5p/Sox4 axis (Gao et al., 2021). Here, SOX4 is linked to liver cancer.