For example, over-expressed miR-1251-5p can inhibit the proliferative, migratory and immunoescape-related abilities of KIRC cells (Yue et al., 2022), and over-expressed miR-486-5p can repress the proliferative ability and promote the apoptosis of KIRC cells (He et al., 2019), while miR-223-3p can facilitate the proliferative and metastatic abilities of renal clear cell carcinoma by downregulating SLC4A4 (Xiao et al., 2019). Here, SLC4A4 is linked to clear cell renal carcinoma.