SLE being an autoimmune disease, over 100 different self-molecules have been known to bind autoantibodies; specifically, ANA, anti-dsDNA, anti-Sm, and antiphospholipid antibodies (APLA) are among the 11 criteria used for diagnosing SLE according to SLICC. The gene discussed is BTG3; the disease is systemic lupus erythematosus.