RNPC3 and arthritic joint disease: ANAs can identify particular subsets of LE; anti-dsDNA is associated with renal involvement, anti-RO/SSA with SCLE rash, serositis, and hematological manifestations, anti-ribosomal P protein with neuropsychiatric disorders, and anti-RNP with arthritis, Raynaud’s phenomenon, and puffy fingers [28].