AGBL3 and rheumatoid arthritis: In addition, because the presence of an anti-CCP3 level of >60 units was associated with increased risk for RA in univariate analysis, and that high level is also given additional points towards RA classification in the 2010 ACR/EULAR criteria, and the presence of the SE was also associated with increased risk for incident IA/RA (Table 1), we further evaluated the relationship between RF positivity and incident IA stratified by baseline anti-CCP3 levels (<=60 or >60), and the presence/absence of the SE (Figures 1B–E).