CD40LG and rheumatoid arthritis: Moreover, we identified in the DoDSR cohrt that women had a higher prevalence than men of RF-IgA and RF-IgM positivity at the earliest available time point pre-RA diagnosis as well as a higher prevalence of RF-IgA and RF-IgM positivity post-RA diagnosis (Supplemental Table 4), although there were no sex-specific differences in autoantibody positivity in the Healthfair cohort (Supplemental Table 5).