ITGAX and inflammatory bowel disease: Visualization of the expression patterns of CD3, CD4, CD7, CD45RO, CD11c, HLA-DR, CD127 and CD161 revealed an even distribution of CD45+ immune cells in the biopsies from control subjects, while they accumulated in certain areas of the inflamed IBD biopsies just below the epithelium (Figures 6A, S6.1 and S6.2).