This analysis of immune markers of different functions T cells showed that CFHR4 expression was highly correlated with the most immunomarkers (CD8B, CD3D, STAT1, IFN-γ, STAT5A, IL21, TGFβ, PD-1, CTLA4, LAG3 and TIM-3) of T cells in HCC (Table 1). This evidence concerns the gene LAG3 and hepatocellular carcinoma.