Despite the finding of an association of a sustained IgM production with chronic renal colonization that was not observed with the Verdun Cl3, we found a limited production of specific Immunoglobulins G (IgG) after infection with Verdun Cl3 compared to Manilae L495 virulent or the M895 avirulent mutant that did not colonize either (10). Here, CD40LG is linked to infection.