Cells in the tetramer-positive fraction were 19.7-fold enriched for proliferating cells (Cluster 5) and 21.7-fold enriched for exhausted cells (Cluster 1), indicating that a substantial fraction of CD8+ T cells involved in response to B16F10 tumors after AIP treatment are specific for the p15E antigen. Here, CD8A is linked to autoimmune pancreatitis.