Consistent with this finding, enrichment of CD8+ T (CD8+ T1, CD8+ T2, and CD8+ T3) cells and DCs (cDC1 and cDC2) in tumor tissue conferred enhanced immune activation and recruitment of antitumor effector cells (32, 33), while the abundance of B cells was fewer in tumor tissue compared to adjacent normal tissue and PBMC. The gene discussed is CD8A; the disease is neoplasm.