STAT3 and neoplasm: The results revealed that the INTERFERON_GAMMA_RESPONSE pathway, the IL2_STAT5_SIGNALING pathway, the TNFA SIGNALING VIA NKFB pathway, the UV_RESPONSE_UP, IL6_JAK_STAT3_SIGNALING pathway, and the HYPOXIA pathway were upregulated in tumor-infiltrating cells (Figure 4F).