Target genes of non-muscle atrophy-related differentially expressed TFs were more likely to be related to carbon metabolism, fatty acid metabolism, TCA cycle, and HIF-1 signaling pathway than the other gene set, while the target genes of muscle atrophy-related differentially expressed TFs were more likely to be related to PI3K–Akt signaling pathway, JAK–STAT signaling pathway, and cytokine–cytokine receptor interaction than the other gene set (Figure 4A). This evidence concerns the gene AKT1 and Atrophy.