LYVE1 and dilated cardiomyopathy: LYVE1+FOLR2+ macrophages are monocyte-derived and express the chemoattractant cytokine genes CCL13 and CCL18. Patients with dilated cardiomyopathy showed reduced numbers of LYVE1+ resident macrophages (subsets expressed FOLR2 and HSPH1) and an increased number of inflammatory macrophages (subsets expressed TREM2, CCL3 and KLF2) (Koenig et al., 2022).