Our findings of inverse associations of rs7672915, intron 2 in subgroups (older age, with renal impairment, and antiplatelet users) could be random findings or due to the role of PPARGC1A in mitochondria subsequently affecting the aging process (Wenz, 2011), kidney disease (Lynch et al., 2018), and platelet function (Melchinger et al., 2019). Here, PPARGC1A is linked to kidney disorder.