In addition, colocalization analysis identified a strong LD between the best eQTL (rs7130173) and the best eQTL (rs6589218, rs6589220, and rs3087967) (1.0 ≥ r2 ≥ 0.8) (Figures 3(c)–3(e)), and with PP4s for causality (C11orf53, PP4 = 0.99; COLCA1, PP4 = 0.99; and COLCA2, PP4 = 0.99, respectively), confirming that the significant CRC GWAS signal and colon transverse eQTL signals share the same variant at its locus. This evidence concerns the gene POU2AF3 and colorectal carcinoma.