GREM1 and colorectal carcinoma: The best eQTL in the locus associated with the expression level of GREM1-AS1 was rs2611583 (PeQTL = 4.42 × 10−4), which is shown to be weak LD with rs1919360 (0.2 ≥ r2 ≥ 0) (Figure 3(f)), while the fifth hypothesis was supported by formal Bayesian colocalization with a PP4 of 0.70 (Table 1), providing modest evidence that significant CRC GWAS signaling and colon sigmoid eQTL signaling share the same variants at their loci.