NEFL and Alzheimer disease: Recent evidence continues to support the idea of a human brain-abundant pathology-associated miRNA-30b in various disease states and the targeting of the NF-L mRNA 3'-UTR that may account, in part, for this decreased output of NF-L mRNA, protein, and expression in LPS-stressed neurons, and have relevance to the altered neuronal signaling capabilities characteristic of AD-affected neurons.