A small subset of NF-kB-regulated miRNAs has been identified and characterized in the AD neocortex and hippocampal CA1 region, and in reactive-oxygen species (ROS)-, cytokine interleukin 1-beta (IL-1β), amyloid-beta 42 (Aβ42) peptide, and/or lipopolysaccharide-(LPS) stressed human neuronal-glial (HNG) cells in primary co-culture (36–49). This evidence concerns the gene IL1B and Alzheimer disease.