At 5 μM curcumin, it reduced apoptosis and inhibited autophagy and hypoxia-inducible factor 1-alpha in rat adrenal pheochromocytoma cell, PC12, model of oxygen-glucose deprivation/reperfusion (OGD/R) condition (Hou, Wang & Feng, 2019). Here, HIF1A is linked to adrenal gland pheochromocytoma.