AAV is primarily categorised into three subtypes such as microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA), and eosinophilic granulomatosis with polyangiitis (EGPA) (2) and it is occasionally classified as myeloperoxidase (MPO)-ANCA vasculitis, proteinase 3 (PR3)-ANCA vasculitis, and ANCA-negative vasculitis (3). The gene discussed is MPO; the disease is granulomatosis with polyangiitis.