Moreover, miR-19b in endothelial MPs (EMPs) induced by hypoxia was shown by a study to be able to reduce endothelial cell migration and angiogenesis by downregulating TGF-β2 expression, which may have inhibited the progression of atherosclerosis (49), indicating that Tgfb2 acts as an intermediate gene to mediate the apoptosis of cardiomyocytes or the progression of atherosclerotic disease. This evidence concerns the gene TGFB2 and atherosclerosis.