Antiphospholipid antibodies (aPL) are detected in nearly half of SARS-CoV-2+ patients, and their prevalence was shown to be even higher in severe ones; but it is still debated if aPL positivity is just an epiphenomenon of an upregulated inflammatory state triggered by COVID-19 or a true player in the thrombotic storm of severe forms [26]. Here, FASLG is linked to COVID-19.