Completely abolishing the SAC, however, is detrimental to human cells (Dobles et al, 2000; Kops et al, 2004; Michel et al, 2004; Schukken et al, 2021), and suppression of the SAC may in fact be a successful therapeutic strategy against some cancer types (Cohen‐Sharir et al, 2021; Quinton et al, 2021). This evidence concerns the gene ADCY10 and cancer.