Of note, we also observed an increase in anti‐inflammatory cytokines (e.g., IL‐10 and TGF‐β1) in the CM of hASCs modified by aging or obesity, which fits with the finding that age‐related inflammation is linked to the presence of some anti‐inflammatory factors in the hASC niche (Zhang et al., 2021). This evidence concerns the gene TGFB1 and obesity due to melanocortin 4 receptor deficiency.