In the HBx‐expressing MHCC97H xenograft tumour tissues, si2R5C treatment decreased the expression of B56γ, upregulated the levels of p‐AKTThr308, p‐AKTSer473, MMP2, and MMP9 in the si2R5C injection group (Figure 5H,I). The gene discussed is MMP9; the disease is neoplasm.