PPP2R5C and hepatocellular carcinoma: These results indicated that B56γ might especially target the dephosphorylation of p‐AKTThr308 and p‐AKTSer473 to negatively regulate the activation of p‐AKT signalling, while and gain‐of‐function of B56γ may represent a potential approach to inhibit the migratory and invasive phenotypes of HBx‐expressing HCC cells.