MAPT and Cognitive impairment: Several published studies have found that hyperphosphorylated Tau proteins in the brain play important roles in anesthesia‐induced cognitive impairment in young mice (Shen et al., 2013; Tao et al., 2014; Vutskits & Xie, 2016), but the underlying mechanisms, particularly the upstream mechanism by which anesthesia‐induced Tau phosphorylation leads to cognitive impairment in young mice, are still unknown.