Further, blocking CXCL9‐CXCR3 signaling by ligand antibodies or the CXCR3 antagonist, NBI‐74330, inhibited osteoclast progenitor recruitment and differentiation.(11, 12) In a medaka fish osteoporosis model suitable for live in vivo imaging, where bone loss was induced by ectopic Rankl expression, we recently elucidated the mechanism behind the critical role of CXCL9 for osteoclast recruitment under experimentally induced osteoporotic conditions.(13, 14) Another chemokine, CXCL10, binds to the same CXCR3 receptor as CXCL9 and has also been implicated in osteoimmuno‐modulating pathways. Here, CXCL9 is linked to osteoporosis.