Interestingly, although CXCL10 was shown to facilitate trafficking of CXCR3‐expressing cancer cells to the bone, which then augmented its own production and promoted osteoclastic differentiation, this was in the context of osteolytic bone metastasis.(15) Finally, when comparing extreme quartiles of CXCL10 in men, although the odds ratio of 2.71 for the risk of hip fracture did not meet the threshold for statistical significance in our study (Table 3), this risk estimate could possibly reach statistical significance in future studies with larger sample sizes. This evidence concerns the gene CXCL10 and cancer.