LINC00473 is a lncRNA downregulated in CRC that exerts tumor suppressor functions in this disease by promoting apoptotic protease-activating factor 1 (APAF1) IRES activity through competitively sponging miR574-5p and miR15b-5p in tumor initiation and pathogenesis [15]. The gene discussed is APAF1; the disease is neoplasm.