Otherwise, small Nucleolar RNA Host Gene 3 (SNHG3), a novel Long non-coding RNA, has been validated that it was concomitant with a variety of cancers, aimed at malignant progression as well as prognosis in vitro and in xenograft vivo, such as hepatocellular carcinoma [92], colorectal cancer [93], ovarian cancer [94]. This evidence concerns the gene SNHG3 and hepatocellular carcinoma.