Of all 505 SNPs (154 loci) not in the APOE locus in AD, NAD, and AD&NAD groups, one locus harboring FXYD5 and FAM187B genes (11 SNPs, NAD group) was on chromosome 19, and the other 494 SNPs (153 loci) were not on chromosome 19. Here, FAM187B is linked to Alzheimer disease.