Concerning tubulo-interstitial lesions, none of the patients with NOS-IgA showed interstitial fibrosis/tubular atrophy (IF/TA) grade 2 or higher lesions, whereas 9 out of 18 cases (50%) with CD-IgAN had grade 2 or higher lesions, suggesting that the CD-IgA group had significantly higher IF/TA grade compared to the NOS-IgAN group (1.50 ± 0.99 vs. 0.36 ± 0.50, p = 0.017), whereas the extent of interstitial inflammatory cell infiltration tended to be higher in the CD-IgAN group than in the NOS-IgAN group but not significantly different (1.17 ± 0.62 vs. 0.64 ± 0.50, p = 0.092). Here, CD79A is linked to Atrophy.