CXCL1 and colorectal carcinoma: To investigate whether FPR1 acts as a negative modulator of angiogenesis also in CRC cells, we treated HT29 and HCT116 cells with fMLF (10−9 m) or with CsH (800 nm) for 3 h and measured the mRNA expression levels of several proangiogenic mediators (VEGF‐A, VEGF‐B, VEGF‐C, VEGF‐D, Ang1 and CXCL1).