WDR62 and coronary artery disorder: WDR62 deficiency was observed to be involved in multiple abnormalities of cardiac development in mice and zebrafish, and to determine the degree of association between WDR62 variants and CHD, we recruited additional human CHD cases corresponding to the types and frequency of heart defects observed in knockout mice: Isolated VSD, TOF, RVD, and another two types of OFT defects—PA+VSD and DORV+PS.