Together, our data suggest that, in agreement with CA STAT signalling identified using IPA, the GHR pathway may be upregulated in GBMGHR high tumours at several levels: GHR transcription (GHRhigh vs. GHRlow PDCL), GHR protein stabilization and GHR signalling (SOCS2 downregulation). The gene discussed is SOAT1; the disease is neoplasm.