Méplan et al. [11] observed a sex-specific differential risk direction for rs2972994-SELENOP, in that rs2972994-SELENOP was not significantly associated with CRC risk for men and women combined, but the authors observed that men with one T allele variant were significantly associated with a higher risk of CRC whereas, in women, the risk of CRC was significantly decreased. Here, SELENOP is linked to colorectal carcinoma.