In this work, plasma and adipocyte levels of anti-inflammatory cytokines (IL-4 and IL-10) were restored in HF-Dia rats and these data reflected the partial restoration of basal inflammatory status in rats supplemented with D. lutheri, suggesting that DHA from D. lutheri, known for its anti-inflammatory effects, increased anti-inflammatory cytokine production [62]. This evidence concerns the gene IL4 and hydrops fetalis.