CASTOR2 was found to be related to the regulation of mTORC1 [28,29,30], a central growth controller that integrates diverse environmental inputs to coordinate anabolic and catabolic processes in cells [31], cancer cells might promote growth transformation and tumorigenesis by manipulating CASTOR2, which was reported in Kaposi sarcoma [32]. The gene discussed is CASTOR2; the disease is Kaposi's sarcoma.