Lutein and zeaxanthin intakes were associated with decreased CRP levels (SMD −0.3 mg/L; 95% CI −0.45, −0.15) [37] and a dose–response relationship found a favorable 17% decreased risk of breast cancer for every 3000 μg/day increase in lutein and zeaxanthin intake (RR 0.83; 95% CI 0.77, 0.89) [29]. The gene discussed is CRP; the disease is breast carcinoma.