BRCA1 and breast cancer: Leading associated risk factors of BC include age, the aggravate prevalence of genetic mutations in predisposition genes (BRCA1 and BRCA2), lifestyle base-modified (non-genetic) risk factors, nulliparity, early menarche, first pregnancy in women older than 30 years of age, older age onset of menopause, usage of oral contraceptives, and personal or familial history of BC and other clinical complaints [4,5,6].