In addition, the incidence of infections after application of bone stimulating factors was not significantly increased in patients who received PRP (I2 = 0%, 95% CI = 2.10 [0.76–5.80], Z = 1.44, p = 0.15), MSCs (I2 = 93%, 95% CI = 0.15 [0.00–9.12], Z = 0.91, p = 0.36), BMP-2 (I2 = 53%, 95% CI = 0.98 [0.56–1.71], Z = 0.08, p = 0.93) or BMP-7 (I2 = 83%, 95% CI = 0.46 [0.03–6.19], Z = 0.58, p= 0.56) for induction of the bone healing process compared with those who did not (Figure 8A–D). Here, BMP7 is linked to infection.