CCL2 and asthma: Monocyte chemotactic protein-1 (MCP-1) is a member of the CC chemokine families and appears to play a relevant role in asthma pathogenesis because of its ability to attract monocytes and eosinophils, as well as activate mast cells and release leukotriene C-4 into the airway, resulting in AHR [71,72].