TNF and Thrombocytopenia: In this phase, a progressive alteration of some inflammatory parameters—such as CRP, ferritin, and pro-inflammatory cytokines (interleukin (IL)-2, IL-6, IL-7, IL-10, colony stimulating factors (GSCF), monocyte chemoattractant protein-1 (MCP-1), macrophage-inflammatory protein (MIP)-1A, and tumor necrosis factor (TNF)-α)—and coagulation parameters, including increased levels of fibrin degradation products such as D-dimer, consumption of coagulation factors, and thrombocytopenia, have been observed [5,6,7,8].