We found the same GLMN variant c.108C > A (p.(Cys36*)), both in a patient with an AVM and in a patient with venous malformations in association with a somatic KRAS variant c.35G > A (p.(Gly12Asp)) and a somatic FGFR3 CNV, respectively. This evidence concerns the gene KRAS and Venous malformation.