According to the histological analyses of the colon (Figure 1C) and score in terms of the severity of inflammation (Figure 1D), DSS-induced colitis was more severe in the distal lesion (4.2 ± 2.9) than in the proximal lesion (0.0) of the wild-type mice on day 8, as previously reported [8]; however, no significant difference was seen in the Ccndbp1-knockout mice, reflecting milder inflammation in the entire colon (Figure 1). Here, CCNDBP1 is linked to colitis.