Similarly, our team showed that advanced HF patients listed for HT with CVP >10 mmHg doubled the likelihood of eGFR < 60 mL/min/1.73 m2 after adjustment for age, history of hypertension, and BNP Z-score, and we found a correlation of eGFR and CVP on a continuous scale [20]. This evidence concerns the gene NPPB and Hypertension.