There was also an observed difference in survival between HF patients with NT-proBNP level > 680 pg/mL and those with an NT-proBNP level ≤ 680 pg/mL (χ2 = 12.7, log rank p = 0.001): eight-year survival was 4% vs. 36%, respectively (Figure 4B). The gene discussed is NPPB; the disease is hydrops fetalis.