Taking into account the rates of mortality with COVID-19 infection, a complementary analysis of multivariate model for the prediction of mortality was fitted using clinical, hematological and biochemical variables associated with the severity and mortality of COVID-19, such as age, sex, peripheral oxygen saturation, C-reactive protein, time of onset of symptoms, neutrophils and lymphocytes levels, anemia, cardiorespiratory disease and immunosuppression. This evidence concerns the gene CRP and COVID-19.